{"id":1830,"date":"2026-05-31T16:49:39","date_gmt":"2026-05-31T08:49:39","guid":{"rendered":"https:\/\/cabit.top\/?p=1830"},"modified":"2026-05-31T16:50:00","modified_gmt":"2026-05-31T08:50:00","slug":"optimising-suitability-criteria-for-bioassay","status":"publish","type":"post","link":"https:\/\/cabit.top\/?p=1830","title":{"rendered":"\u4f18\u5316\u751f\u7269\u6d4b\u5b9a\u9002\u7528\u6027\u6807\u51c6"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u4f5c\u8005\uff1aNick Bryan | Jason Segall<\/p>\n\n\n\n<p 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https:\/\/cabit.top\/wp-content\/uploads\/2026\/05\/image-37-768x512.png 768w, https:\/\/cabit.top\/wp-content\/uploads\/2026\/05\/image-37-670x447.png 670w, https:\/\/cabit.top\/wp-content\/uploads\/2026\/05\/image-37.png 1223w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">\u6d4b\u5b9a\u8303\u56f4\u548c\u6a21\u578b\u6e10\u8fd1\u7ebf\u662f\u76f8\u5173\u7684\uff0c\u8fd9\u610f\u5473\u7740\u540c\u65f6\u6d4b\u91cf\u4e24\u8005\u7684\u68c0\u9a8c\u5f88\u53ef\u80fd\u4f1a\u540c\u65f6\u901a\u8fc7\u548c\u5931\u8d25\u3002<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"images\/optimising-suitability\/Correllation.png\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a>\u5047\u8bbe\u60a8\u5bf9\u4e0a\u4e0b\u6e10\u8fd1\u7ebf\u90fd\u8bbe\u7f6e\u4e86\u8fd9\u6837\u7684\u68c0\u9a8c\uff0c\u540c\u65f6\u8fd8\u5bf9\u6d4b\u5b9a\u8303\u56f4\uff08\u5373\u6e10\u8fd1\u7ebf\u4e4b\u95f4\u7684\u5dee\u503c\uff09\u8bbe\u7f6e\u4e86\u68c0\u9a8c\u3002\u8fd9\u5c06\u662f\u4e00\u4e2a\u76f8\u5173\u68c0\u9a8c\u7684\u793a\u4f8b\uff0c\u56e0\u4e3a\u6d4b\u5b9a\u8303\u56f4\u672c\u8d28\u4e0a\u662f\u7531\u4e0a\u4e0b\u6e10\u8fd1\u7ebf\u5b9a\u4e49\u7684\u3002\u5982\u679c\u6d4b\u8bd5\u6837\u54c1\u7684\u8303\u56f4\u4e0e\u53c2\u6bd4\u54c1\u7684\u4e0d\u540c\uff0c\u90a3\u4e48\u51e0\u4e4e\u53ef\u4ee5\u80af\u5b9a\u81f3\u5c11\u6709\u4e00\u6761\u6e10\u8fd1\u7ebf\u4e5f\u4e0d\u540c\uff0c\u8fd9\u610f\u5473\u7740\u4e24\u4e2a\u68c0\u9a8c\u5f88\u53ef\u80fd\u540c\u65f6\u5931\u8d25\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u5bf9\u4e8e\u975e\u5e38\u7cbe\u5bc6\u7684\u6d4b\u5b9a\uff0c\u7eaf\u8bef\u5dee\u603b\u662f\u5f88\u5c0f\uff0c\u8fd9\u610f\u5473\u7740\u5931\u62df\u8bef\u5dee\u5c06\u5360\u4e3b\u5bfc\u5730\u4f4d\u3002\u8fd9\u53ef\u80fd\u5bfc\u81f4\u6d4b\u5b9a\u672a\u901a\u8fc7 F \u68c0\u9a8c\uff0c\u5373\u4f7f\u4ece\u4efb\u4f55\u5176\u4ed6\u8861\u91cf\u6807\u51c6\u6765\u770b\uff0c\u6211\u4eec\u90fd\u671f\u671b\u5b83\u901a\u8fc7\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4ec0\u4e48\u8ff9\u8c61\u8868\u660e F \u68c0\u9a8c\u53ef\u80fd\u4e0d\u9002\u7528\u4e8e\u60a8\u7684\u6d4b\u5b9a\uff1f\u5982\u679c\u60a8\u9884\u8ba1\u6d4b\u5b9a\u5c06\u6709\u5f88\u9ad8\u7684\u7cbe\u5bc6\u5ea6\u2014\u2014\u4f8b\u5982\uff0c\u5982\u679c\u60a8\u4f7f\u7528\u673a\u5668\u4eba\u8fdb\u884c\u6d4b\u5b9a\u70b9\u6837\u2014\u2014\u90a3\u4e48\u6700\u597d\u907f\u514d\u4f7f\u7528 F 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\u80fd\u66f4\u597d\u5730\u62df\u5408\u8be5\u6570\u636e\u3002\u5982\u679c\u6211\u4eec\u671f\u671b\u6570\u636e\u7b26\u5408 4PL\uff0c\u90a3\u4e48\u8fd9\u53ef\u80fd\u8868\u660e\u51fa\u73b0\u4e86\u95ee\u9898\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"582\" src=\"https:\/\/cabit.top\/wp-content\/uploads\/2026\/05\/image-38-1024x582.png\" alt=\"\" class=\"wp-image-1833\" srcset=\"https:\/\/cabit.top\/wp-content\/uploads\/2026\/05\/image-38-1024x582.png 1024w, https:\/\/cabit.top\/wp-content\/uploads\/2026\/05\/image-38-300x170.png 300w, https:\/\/cabit.top\/wp-content\/uploads\/2026\/05\/image-38-768x436.png 768w, https:\/\/cabit.top\/wp-content\/uploads\/2026\/05\/image-38-670x381.png 670w, https:\/\/cabit.top\/wp-content\/uploads\/2026\/05\/image-38.png 1225w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">\u5728\u8fd9\u91cc\uff0c\u6211\u4eec\u770b\u5230\u9ad8\u5242\u91cf\u5904\u7684\u54cd\u5e94\u63a5\u8fd1\u4e8e\u96f6\u3002\u5982\u679c\u9002\u7528\u6027\u6807\u51c6\u662f\u57fa\u4e8e\u6d4b\u8bd5\u6837\u54c1\u548c\u53c2\u6bd4\u54c1\u6e10\u8fd1\u7ebf\u7684\u6bd4\u503c\u8bbe\u5b9a\u7684\uff0c\u90a3\u4e48\u5f88\u53ef\u80fd\u4f1a\u770b\u5230\u4e0d\u5fc5\u8981\u7684\u5931\u8d25\u3002<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"images\/optimising-suitability\/Inappropriate.png\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a>\u53e6\u4e00\u4e2a\u7ecf\u5e38\u88ab\u8bc1\u660e\u4e0d\u6070\u5f53\u7684\u9002\u7528\u6027\u6807\u51c6\u793a\u4f8b\u662f\u57fa\u4e8e\u6a21\u578b\u53c2\u6570\u6bd4\u503c\u7684\u6807\u51c6\uff0c\u8fd9\u4e9b\u6807\u51c6\u901a\u5e38\u7528\u4e8e\u68c0\u9a8c\u5e73\u884c\u6027\u3002\u5982\u679c\u6240\u9009\u53c2\u6570\u7684\u6bd4\u503c\u63a5\u8fd1 1\uff0c\u5219\u8868\u660e\u53c2\u6bd4\u54c1\u548c\u6d4b\u8bd5\u6837\u54c1\u4e4b\u95f4\u5b58\u5728\u76f8\u4f3c\u6027\u3002\u7136\u800c\uff0c\u5982\u679c\u5176\u4e2d\u4e00\u4e2a\u53c2\u6570\u901a\u5e38\u63a5\u8fd1\u96f6\uff0c\u8fd9\u53ef\u80fd\u4f1a\u5e26\u6765\u95ee\u9898\uff0c\u56e0\u4e3a\u9664\u4ee5\u4e00\u4e2a\u5c0f\u6570\u53ef\u80fd\u4f1a\u5f97\u5230\u4e00\u4e2a\u8fdc\u5927\u4e8e 1 \u7684\u7ed3\u679c\uff0c\u5373\u4f7f\u6a21\u578b\u53c2\u6570\u4e4b\u95f4\u7684\u5dee\u5f02\u5f88\u5c0f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8fd9\u4e2a\u95ee\u9898\u7ecf\u5e38\u51fa\u73b0\u7684\u4e00\u79cd\u60c5\u51b5\u662f\uff0c\u6d4b\u5b9a\u5728\u4f4e\u5242\u91cf\u4e0b\u7684\u54cd\u5e94\u63a5\u8fd1\u4e8e\u96f6\u3002\u5982\u679c\u9009\u62e9\u4e86\u57fa\u4e8e\u4e0b\u6e10\u8fd1\u7ebf\u53c2\u6570\u6bd4\u503c\u7684\u9002\u7528\u6027\u6807\u51c6\uff0c\u90a3\u4e48\u5f88\u53ef\u80fd\u4f1a\u7531\u4e8e\u53c2\u6570\u6bd4\u503c\u800c\u770b\u5230\u4e0d\u5fc5\u8981\u7684\u6d4b\u5b9a\u5931\u8d25\u3002\u56e0\u6b64\uff0c\u6211\u4eec\u901a\u5e38\u5efa\u8bae\u4f7f\u7528\u53c2\u6570\u4e4b\u95f4\u7684<em>\u5dee\u503c<\/em>\u800c\u4e0d\u662f\u6bd4\u503c\uff0c\u56e0\u4e3a\u5dee\u503c\u4e0d\u4f1a\u50cf\u53c2\u6570\u6bd4\u503c\u90a3\u6837\u6709\u88ab\u653e\u5927\u7684\u8d8b\u52bf\u3002\u56e0\u6b64\uff0c\u68c0\u9a8c\u53c2\u6570\u5dee\u503c\u800c\u975e\u6bd4\u503c\u662f\u907f\u514d\u4e0d\u5fc5\u8981\u6d4b\u5b9a\u5931\u8d25\u7684\u597d\u65b9\u6cd5\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u7ee7\u7eed\u9605\u8bfb&#8230;<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.quantics.co.uk\/blog\/bioassay-optimisation-save-time-save-money\/\">\u751f\u7269\u6d4b\u5b9a\u4f18\u5316\uff1a\u8282\u7701\u65f6\u95f4\uff0c\u8282\u7701\u91d1\u94b1<\/a><a href=\"https:\/\/www.quantics.co.uk\/blog\/how-to-set-suitability-criteria-for-relative-potency-bioassays\/\">\u5982\u4f55\u4e3a\u76f8\u5bf9\u6548\u4ef7\u751f\u7269\u6d4b\u5b9a\u8bbe\u7f6e\u9002\u7528\u6027\u6807\u51c6<\/a><a href=\"https:\/\/www.quantics.co.uk\/blog\/r%c2%b2-ii-what-should-you-use-to-measure-goodness-of-fit\/\">R\u00b2 II\uff1a\u4f60\u5e94\u8be5\u7528\u4ec0\u4e48\u6765\u6d4b\u91cf\u62df\u5408\u4f18\u5ea6\uff1f<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u5bfb\u627e\u6700\u4f18\u89e3\u51b3\u65b9\u6848<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u751f\u7269\u6d4b\u5b9a\u662f\u590d\u6742\u7684\u5b9e\u9a8c\uff0c\u9700\u8981\u5927\u91cf\u8d44\u6e90\u2014\u2014\u65e0\u8bba\u662f\u4eba\u5458\u65b9\u9762\u8fd8\u662f\u8d44\u91d1\u65b9\u9762\u2014\u2014\u624d\u80fd\u6709\u6548\u5730\u5f00\u53d1\u548c\u8fd0\u884c\u3002\u6ca1\u6709\u4e24\u4e2a\u6d4b\u5b9a\u662f\u5b8c\u5168\u76f8\u540c\u7684\uff0c\u8fd9\u610f\u5473\u7740\u5bf9\u4e00\u4e2a\u6d4b\u5b9a\u800c\u8a00\u7684\u6700\u4f73\u89e3\u51b3\u65b9\u6848\u53ef\u80fd\u4f1a\u5bf9\u4e0b\u4e00\u4e2a\u6d4b\u5b9a\u9020\u6210\u65e0\u7a77\u65e0\u5c3d\u7684\u9ebb\u70e6\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c\u6211\u4eec\u5e0c\u671b\u672c\u6587\u4e2d\u63d0\u51fa\u7684\u5efa\u8bae\u80fd\u591f\u542f\u53d1\u5927\u5bb6\u601d\u8003\uff0c\u5982\u4f55\u901a\u8fc7\u5bf9\u9002\u7528\u6027\u6807\u51c6\u505a\u51fa\u5ba1\u614e\u9009\u62e9\u6765\u4f18\u5316\u6d4b\u5b9a\u8bbe\u8ba1\u3002\u800c\u4e14\uff0c\u5982\u679c\u60a8\u9700\u8981\u4efb\u4f55\u8fdb\u4e00\u6b65\u7684\u6307\u5bfc\uff0cQuantics \u968f\u65f6\u4e3a\u60a8\u63d0\u4f9b\u5e2e\u52a9\uff01<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Nick Bryan<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Nick \u662f Quantics Biostatistics \u7684\u8d44\u6df1\u7edf\u8ba1\u5e08\u3002\u4ed6\u4e3a\u5ba2\u6237\u63d0\u4f9b GxP \u7814\u7a76\u3001\u751f\u7269\u6d4b\u5b9a\u8bbe\u8ba1\u4ee5\u53ca\u4e34\u5e8a\u548c\u975e\u4e34\u5e8a\u7814\u7a76\u5206\u6790\u65b9\u9762\u7684\u652f\u6301\u3002\u4ed6\u66fe\u5728 Ipsen Biopharm \u548c Sanofi \u5de5\u4f5c\uff0c\u5728\u751f\u7269\u5236\u54c1\u548c\u5c0f\u5206\u5b50\u9886\u57df\u62e5\u6709\u4e30\u5bcc\u7ecf\u9a8c\u3002\u4ed6\u62e5\u6709\u6570\u636e\u79d1\u5b66\u4e0e\u4eba\u5de5\u667a\u80fd\u7855\u58eb\u5b66\u4f4d\u4ee5\u53ca\u795e\u7ecf\u79d1\u5b66\u5b66\u58eb\u5b66\u4f4d\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Jason Segall<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Jason \u4e8e 2022 \u5e74\u52a0\u5165 Quantics \u5e02\u573a\u56e2\u961f\u3002\u4ed6\u62e5\u6709\u7406\u8bba\u7269\u7406\u5b66\u548c\u79d1\u5b66\u4f20\u64ad\u7855\u58eb\u5b66\u4f4d\uff0c\u5e76\u62e5\u6709\u591a\u5e74\u7684\u5728\u7ebf\u79d1\u5b66\u4f20\u64ad\u548c\u535a\u5ba2\u5199\u4f5c\u7ecf\u9a8c\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4f5c\u8005\uff1aNick Bryan | &#46;&#46;&#46;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-1830","post","type-post","status-publish","format-standard","hentry","category-basicknow"],"_links":{"self":[{"href":"https:\/\/cabit.top\/index.php?rest_route=\/wp\/v2\/posts\/1830","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cabit.top\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cabit.top\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cabit.top\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cabit.top\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1830"}],"version-history":[{"count":2,"href":"https:\/\/cabit.top\/index.php?rest_route=\/wp\/v2\/posts\/1830\/revisions"}],"predecessor-version":[{"id":1834,"href":"https:\/\/cabit.top\/index.php?rest_route=\/wp\/v2\/posts\/1830\/revisions\/1834"}],"wp:attachment":[{"href":"https:\/\/cabit.top\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1830"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cabit.top\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1830"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cabit.top\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1830"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}